| 1920 |
Nakashima Shigeru Shoten was founded as an importer and distributor of pharmaceuticals and medical devices in Manila, the Republic of Philippines. |
| 1923 |
Started business as a pharmaceuticals developer and manufacturer under the name of Sansho Co., Ltd. |
| 1933 |
医薬品の開発と製造を目的に三生製薬株式会社として創業 |
| 1933 |
The business expanded due to the success of the liver oil tablet, 'Haliva.' |
| 1934 |
フィリピン、マニラ市に、医薬品・医療機器等の現地輸入販売業「中島茂商店」を創立 |
| 1939 |
Incorporated Osaka Office into Nakashima Shigeru Shoten. |
| 1946 |
大阪支店を「株式会社中島茂商店」に改組設立 |
| 1952 |
Corporate name changed to Nippon Shoji Kaisha, Ltd. |
| 1965 |
Started full-scale production of pharmaceuticals for Eisai Co., Ltd. |
| 1968 |
Became a subsidiary of Eisai Co., Ltd. |
| 1986 |
Eisai Co., Ltd. released the medicine for iron-deficiency, anemia, developed by ourself. |
| 1989 |
Acquired an authorization of contract manufacturing from Eisai Co., Ltd. |
| 1996 |
Transitioned into a large company under commercial law based on increased capital. |
| 1997 |
Started production of barrier-free medicines, marketed by Elmed Eisai Co., Ltd. Acquired a manufacturing authorization of liquid-, ointment-, and cream-form medicines from Eisai Co., Ltd. |
| 1998 |
中国山東省に青島耐絲克医材有限公司を設立 |
| 1998 |
Nippon Shoji and Showa Pharmaceuticals merged to form AZWELL Inc. |
| 1998 |
Relocated the headquarters to Serada-Cho, Ota City, Gunma (previously known as Ojima-machi, Nitta-gun). |
| 1999 |
Completed relocation of whole company to Serada-Cho, Ota City, Gunma. Changed the corporate name to Sannova Co., Ltd. |
| 2001 |
Obtained the ISO 14001 certification. |
| 2003 |
日本商事株式会社と昭和薬品株式会社が合併し、株式会社アズウェル誕生 |
| 2003 |
AZWELL Inc. and Fukujin Co., Ltd. established Alfresa Holdings Corporation through stock transfer. |
| 2004 |
福神株式会社と経営統合し、共同持株会社アルフレッサ ホールディングス株式会社を設立 |
| 2004 |
Alfresa Pharma Corporation was established. |
| 2004 |
Established new drainage treatment facilities. |
| 2006 |
Ibaraki Research Center, Okayama Plant, and Chiba Plant obtained the ISO13485:2003 certification. |
| 2015 |
Took over the Akita Plant of Daiichi Sankyo Propharma Co., Ltd., and establishes Alfresa Fine Chemical Corporation. |
| 2016 |
Sannova Co., Ltd. became a wholly owned subsidiary of Alfresa Holdings Corporation. |
| 2023 |
Alfresa Pharma Corporation and Sannova Co., Ltd. merges their operations. |