HISAMITSU PHARMACEUTICAL CO.,INC.

1847: Founded Komatsuya (Hisamitsu Jinpei)

1847 (Kōka 4) year

Founded Komatsuya (Hitoshi Hisamitsu)

Founded: 1847 (Kōwa 4)

1869: Launched 'Kishindan: ® :'

Launch of "Kishindan : ® : "

1871: Renamed from Komatsuya to Hisamitsu Jōeidō (Hisamitsu Yoichi)

Renamed from Komatsuya to Hisamitsu Jōeido (Yoshii Hisamitsu)

1903: Established Hisamitsu Brothers General Partnership (President Saburō Nakato)

Establishment of Hisamitsu Brothers General Partnership (President Saburo Nakato)

1907: Launched 'Asahi Bankin-kō: ® :'

Launch of "Asahi Bankinko : ® : "

1934: Launched 'Salonpas: ® :'

Launch of "Salonpas : ® : "

1944: Hisamitsu Brothers General Partnership established the controlled company Sanyōki Seiyaku Co., Ltd.

Hisamitsu Brothers General Partnership established the controlled company Sanyo Pharmaceutical Co., Ltd.

May 22, 1944 (Showa 19)

Established: May 22, 1944 (Showa 19)

1951: Established Hisamitsu Brothers Co., Ltd. (President Masayoshi Nakato)

Establishment of Hisamitsu Brothers Corporation (President Masayoshi Nakato)

1952: Opened Osaka Branch (current branch)

Established Osaka Branch (Current Branch Office)

1957: Opened Tokyo Branch (current Tokyo Head Office and branch)

Established Tokyo Branch (Current Tokyo Head Office & Branch)

1960: Established Hisamitsu Pharmaceutical Taiwan Branch (current Taipei Branch)

Established Kosei Pharmaceutical Co., Ltd. (Taiwan) (Current Taipei Branch)

1962: Listed on the Second Section of the Tokyo Stock Exchange and Fukuoka Stock Exchange

Listed on the Second Section of the Tokyo Stock Exchange and Fukuoka Stock Exchange

1963: Launched 'Air: ® : Salonpas: ® :'

Launched "Air : ® : Salonpas : ® : "

1964: Listed on the Second Section of the Osaka Securities Exchange

Listed on the Second Section of the Osaka Securities Exchange

1965: Renamed to Hisamitsu Pharmaceutical Co., Inc.

Renamed to Kosei Pharmaceutical Co., Ltd.

Showa 41 (1966): Nagoya Branch Office Opened (Current Branch)

Established Nagoya Branch (Current Branch Office)

Showa 43 (1968): Launch of 'Salonpas: ® : E'

Launched "Salonpas : ® : E"

Showa 45 (1970): Sapporo Branch Office Opened (Current Branch)

Established Sapporo Branch (Current Branch Office)

Showa 46 (1971): Launch of 'Salonship: ® :': Listed on the Second Section of Nagoya Stock Exchange: Tosu Research Institute Completed: Sendai Branch Office Opened (Current Branch)

Launched "Salonship : ® : ", Listed on the Second Section of Nagoya Securities Exchange, Completed Tori Research Institute, Established Sendai Branch (Current Branch)

Showa 47 (1972): Reassigned to the First Section of TSE, OSE, and Nagoya Stock Exchange: Launch of 'Papp Salon: ® :'

Reclassified to the First Section of the Tokyo, Osaka, and Nagoya Exchanges; Launched "Papp Salon : ® : "

Showa 50 (1975): Establishment of P.T. Salonpas Indonesia (Indonesia)

Established P.T. Salonpas Indonesia (Indonesia)

Showa 53 (1978): Launch of 'Papp Salon G: ® :'

Launched "Papp Salon G : ® : "

Showa 56 (1981): Masayoshi Nakato appointed Director and Chairman, Hirotaka Nakato appointed President and CEO

Justice Nakato appointed Chairman of the Board and Hirotaka Nakato appointed President and Representative Director

Showa 57 (1982): Launch of 'Salonpas-High: ® :'

Launched "Salonpas-High : ® : "

Showa 58 (1983): Takamatsu Branch Office Opened (Current Sales Office): Hiroshima Branch Office Opened (Current Branch)

Established Takamatsu Branch (Current Sales Office); Established Hiroshima Branch (Current Branch)

Showa 59 (1984): Launch of 'Vesicame: ® : (Ointment, Cream)'

Launched "Vesicame : ® : (Ointment & Cream)"

Showa 60 (1985): Launch of 'Salonpas A: ® :'

Launched "Salonpas A : ® : "

Showa 61 (1986): Establishment of Hisamitsu Farmaceutica do Brasil Limitada (Brazil): Launch of 'Salonpas 30: ® :': Launch of 'Holes Salonpas A: ® :': Launch of 'Sector Gel: ® :'

Established Hisamitsu Pharmacutica do Brasil Limitada (Brazil); Launched "Salonpas 30 : ® : ", Launched "Holes Salonpas A : ® : ", Launched "Sector Gel : ® : "

Showa 62 (1987): Establishment of Hisamitsu America Incorporated (USA): Launch of 'Nobinobi: ® : Salonship: ® :': Utsunomiya Factory Completed

HISAMITSU America Incorporated established (USA): "Nobi Nobi: ®: Salonship: ®:" launched: Utsunomiya Factory completed

Showa 63 (1988): Establishment of the Masayoshi Nakato Health Science Promotion Foundation: Launch of 'Moras: ® :'

Foundation of the Nakato Health Science Promotion Foundation: *"MORAS: ®:" launched

Heisei 1 (1989): Use of new logo mark 'HISAMITSU': Launch of 'Sector: ® : Lotion and Cream'

Use of "HISAMITSU" new logo mark: *"Sector: ®: Lotion & Cream" launched

Heisei 2 (1990): Completion of Tsukuba Research Institute: Establishment of the Masayoshi Nakato Memorial Foundation

Construction of Tsukuba Research Institute: Foundation of Nakato Memorial Foundation

Heisei 3 (1991): Launch of 'Air: ® : Salonpas: ® : EX'

Launch of "Air: ®: Salonpas: ®: EX"

Heisei 4 (1992): Launch of 'Boree: ® : (Cream, Liquid)'

*"Boree: ®: (Cream & Liquid)" launched

Heisei 5 (1993): Launch of 'Salonship: ® : Heat Therapy Equipment'

Launch of "Salonship: ®: Heat Therapy Device"

Heisei 6 (1994): Change of 'HISAMITSU' logo mark: Hisamitsu Pharmaceutical KBC Augusta held: Establishment of Hisamitsu Vietnam Pharmaceutical Company Limited (Vietnam)

Change of "HISAMITSU" logo mark: Hisamitsu Pharmaceutical KBC Augusta held: Hisamitsu Vietnam Pharmaceutical Company Limited established (Vietnam)

Heisei 7 (1995): Opening of the Hisamitsu Memorial Drug Museum: Operation of Hisamitsu Vietnam Factory: Launch of 'Morlas: ®: Tape'

Opening of Nakato Memorial Medicine Museum: Hisamitsu Vietnam Factory operational: *"MORAS: ®: Tape" launched

Heisei 9 (1997): Launch of 'Salonpas AE: ®:'; Launch of 'Lifecella Face Mask: ®:'

Launch of "Salonpas AE: ®:": Launch of "Lifesera Face Mask: ®:"

Heisei 10 (1998): Establishment of Hisamitsu California Laboratory (USA): Launch of 'Nobinobi: ®: Salonship: ®: α'; Opening of Kumamoto Sales Office; Establishment of London Office (now Hisamitsu UK); Launch of 'La Salonpas: ®:'

Establishment of Hisamitsu California Research Institute (USA): "Nobi Nobi: ®: Salonship: ®: α" launched: Kumamoto Sales Office opened: London Office established (current Hisamitsu UK): "La Salonpas: ®:" launched

Heisei 11 (1999): Acquisition of ISO 14001 (Kyushu Headquarters)

ISO 14001 certification obtained (Kyushu Headquarters)

Heisei 12 (2000): Opening of Kyoto Sales Office; Launch of 'Estrona: ®:'; Acquisition of ISO 14001 (Utsunomiya Factory)

Kyoto Sales Office opened: *"Estrona: ®:" launched: ISO 14001 certification obtained (Utsunomiya Factory)

Heisei 13 (2001): Relocation of Tokyo Headquarters to Marunouchi, Tokyo

Tokyo Headquarters relocated to Marunouchi, Tokyo

Heisei 14 (2002): Establishment of Hisamitsu UK Limited (UK); Launch of 'Lifecella: ®: Beauty Serum Mask'; Operation of Hisamitsu Brazil Manaus Factory; Launch of 'Morlas: ®: Tape L'; Opening of Malaysia Office (Malaysia)

Hisamitsu UK Limited established (UK): "Lifesera: ®: Serum Mask" launched: Hisamitsu Brazil Manaus Factory operational: *"MORAS: ®: Tape L" launched: Malaysia Office opened (Malaysia)

Heisei 15 (2003): Launch of 'Butenalock: ®:'; Opening of Taipei Branch (Taiwan); Change of 'Hisamitsu' logo mark; Launch of 'Flex: ®:'; Launch of 'Fetast: ®:'

Launch of "ButeNaro: ®:": Taipei Branch opened (Taiwan): Change of "Hisamitsu" logo mark: *"Flex: ®:" launched: "Fetast: ®:" launched

Heisei 16 (2004): Opening of Honorary Consulate of the Federative Republic of Brazil; Launch of 'Air: ®: Salonpas: ®: Indomethacin 1.0%'

Honorary Consulate of the Federative Republic of Brazil opened: Launch of "Air: ®: Salonpas: ®: Indomethacin 1.0%"

Heisei 17 (2005): Spin-off of S.S. Pharmaceutical's medical pharmaceuticals business (establishment of Hisamitsu Medical); Launch of 'Keplat: ®:' (Italy); Launch of 'Mohrus: ®: Patch' (Hong Kong); Hosting of Salonpas World Ladies Golf Tournament (now LPGA Tour World Ladies Championship Salonpas Cup); Opening of New Jersey Office; Launch of 'Morlas: ®: 60'; Launch of 'Salonship: ®: L'

Divestiture of S.S. Pharmaceutical Medical Drugs Business (Hisamitsu Medical established): *"KEPLAT: ®:" launched (Italy): *"MOHRUS: ®: PATCH (MORAS: ®: PATCH)" launched (Hong Kong): Salonpas World Ladies Golf Tournament held: (Current LPGA Tour World Ladies Championship Salonpas Cup): New Jersey Office opened: *"MORAS: ®: 60" launched: "Salonship: ®: L" launched

Heisei 18 (2006): Launch of 'Nobinobi: ®: Salonship: ®: s'; Launch of 'Lifecella: ®: Gel Mask'; Launch of 'Fetast: ®: (Lotion, Cream, Ticks)'; Launch of 'Trobeterol Tape HMT'; Launch of 'Naboll: ®: Patch'; Opening of Rome Office (Italy); Opening of Kagoshima Branch; Launch of 'Naboll: ®: Tape L'

Launch of "Nobi Nobi: ®: Salonship: ®: s": Launch of "Lifesera: ®: Gel Mask": Launch of "Fetast: ®: (Lotion, Cream, Ticks)": *"Troboterol Tape 'HMT'" launched: *"Naboll: ®: Papp" launched: Rome Office opened (Italy): Kagoshima Branch opened: *"Naboll: ®: Tape L" launched

Heisei 19 (2007): 160th Anniversary of founding; Launch of 'Lifecella: ®: Emulsion Mask'; Opening of Singapore Branch; Launch of 'Fetast: ®: L'; Launch of 'Salonpas: ®: Lotion'; Establishment of CSR Promotion Office; Completion of Second Utsunomiya Factory; Launch of 'Fetast: ®: Warm'; Introduction of NAS Battery

Founded 160 years ago: Launch of "Lifesera: ®: Emulsion Mask": Singapore Branch opened (Singapore): "Fetast: ®: L" launched: "Salonpas: ®: Lotion" launched: CSR Promotion Office established: Utsunomiya Factory Second Plant completed: "Fetast: ®: Warmth" launched: NAS Battery introduced

Heisei 20 (2008): FDA approval of 'Salonpas: ®: Pain Relief Patch' (USA); Launch of 'Butenalock: ®: V'; Launch of 'Air: ®: Salonpas: ®: DX'; Launch of 'Fetast: ®: L Warm'; Launch of 'Fetast: ®: (Gel, Ticks EX, Ship)'; Launch of 'Lifecella: ®: Beauty Serum Mask Good Skin, Transparent Skin, Glossy Skin'; Launch of 'Salonpas: ®: EX'; Launch of 'Gankyojun: ®:'

"Salonpas®: Pain Relief Patch" FDA approval obtained (United States): "Butenolock®: V" launched: "Air®: Salonpas®: DX" launched: "Faitas®: L Warmth" launched: "Faitas®: (Gel, Chikku EX, Ship)" launched: "Lifecella®: Beauty Serum Mask Good Moisture, Transparent Skin, Glossy Skin" launched: "Salonpas®: EX" launched: "Gankyojun®" launched

Launch of 'Lifecella: ®: Focus on Eyes: ®: Puru-n to Moist, Plump Lift, Firmness and Shine Wrinkle'; Launch of 'Hisamitsu: ®: Icing Sheet'; Launch of 'Air: ®: Salonpas: ®: Icing Spray'; Launch of 'Coleston: ®:'; Establishment of Hisamitsu US Incorporated (USA); Launch of 'Fetast: ®: Z (Tape, Ship, Gel)'; Launch of 'Fetast: ®: Ship Warm'

Launch of 'Butenalock: ®: V Air: ®: Refreshing Powder'; Launch of 'Hisamitsu: ®: Ista Towel'; Launch of 'Fentanyl Transdermal System' (USA); Launch of 'Fentos: ®: Tape'

*Launch of "Norspan : ® : Tape" : Establishment of Hokuetsu Pharmaceutical Technology Consulting (Beijing) Co., Ltd. (China)

*"Norspan®: Tape" launched: Kosei Pharmaceutical Technology Consulting (Beijing) Co., Ltd. established (China)

Launch of "Butenalock : ® : Vα" : Launch of *"Fentanyl 3-day Tape "HMT"" : Launch of "Allegra : Ⓡ : FX"

Relocation of Tokyo headquarters to Marunouchi Building : Launch of "Neoxy : ® : Tape" : Launch of "Fetast : ® : 5.0" : Launch of "Abstral : ® : Sublingual Tablets"

Received the 2014 National Invention Award "Director-General of the Patent Office Award" : Launch of "Fetast : ® : Z Jiksax" : Launch of "Fetast : ® : 5.0 Warm Sensation"

Hirotaka Nakato appointed as Chairman and CEO : Kazuhide Nakato appointed as President and COO : Launch of "Fetast : ® : Medical Supporter" : Simultaneous release of "Salonpas : ® : " in Japan and the US : Opening of Manila Branch (Philippines) : Completion of new factory of P.T. Hisamitsu Pharma Indonesia : Launch of "Moras : ® : Papp XR120mg"

Launch of "Nobinobi : ® : Salonship : ® : F" : 170th Anniversary of Founding : Establishment of Hisamitsu Pharmaceutical (China) Co., Ltd. (China)

"Nobinobi®: Salonship®: F" launched: 170th anniversary of founding: Kosei Pharmaceutical (China) Co., Ltd. established (China)

Tokyo 2020 Olympic and Paralympic Games : Official Partner (External Pain Relief and Anti-inflammatory Drugs) : Establishment of Hisamitsu Pharmaceutical (Hong Kong) Co., Ltd. : Launch of "Aresaga : ® : Tape"

Establishment of Hisamitsu Italy S.r.l. (Italy) : Completion of Hisamitsu Museum : Launch of "Fetast : ® : Zα Jiksax : ® : Gel" : Launch of "Haruropi : ® : Tape"

Establishment of Hisamitsu Pharmaceutical Malaysia Sdn.Bhd. (Malaysia) : Launch of "Secuado : ® : " (USA) : Establishment of Saga Hisamitsu Springs Co., Ltd. (Saga)

Hisamitsu Pharmaceutical Malaysia Sdn.Bhd. established (Malaysia): *"Secuado®" launched (United States): SAGA Hisamitsu Springs Co., Ltd. established (Saga)

Launch of "Jiktor : ® : Tape" : Launch of "Nobinobi : ® : Salonship Fit : ® : 10 pieces (Pokeshop : ® : )"