Kyowa Kirin Korea Co., Ltd.

Dr. Shibasaburo Kitasato and Dr. Bering discovered that the serum obtained from an animal infected with diphtheria was effective in the treatment of diphtheria and tetanus; they established serum therapy.

Establishment of Kirin Brewery Co., Ltd.

Establishment of Kyowa Hakko Kogyo Co., Ltd. as a secondary company of Kyowa Sangyo Co., Ltd, as part of industrial readjustment plans.

Introduced production technology of Streptomycin, an anti-tubercular drug, from US pharmaceutical company Merck & Co., Inc. and succeeded in its mass production. Contributed to the wiping out of tuberculosis in Japan (beginning of involvement in pharmaceutical business operations).

Success of isolation and commercially mass-production of the anticancer drug, Mitomycin C. Invention of the process of L-glutamic acid production by fermentation (a world first).

Gerald Edelman and Rodney Porter determined the molecular structure of antibodies.

Initiation of full-scale involvement in the pharmaceutical business. Release of Mitomycin C, an anticancer drug, and Spiramycin, an antibiotic drug.

Release of 5-FU, an anticancer drug.

Release of Leunase, an anticancer drug.

César Milstein, Georges Köhler and Niels Kaj Jerne established the hybridoma technology, which is a technology for producing monoclonal antibodies.

Dr. Susumu Tonegawa discovered the genetic principle for the generation of antibody diversity.

The Research Institute for Production Development foundation begins full-scale research towards the commercialization of erythropoietin.

The world's first therapeutic antibody "muromonab" was approved.

Supported the establishment in the U.S.A. of the La Jolla Institute for Allergy and Immunology (LIAI).

Release of ESPO®, an erythropoietin (EPO) drug.

Antibody engineering technologies were established.

Release of GRAN®, G-CSF drug. Release of Coniel, a remedy for hypertension and angina pectoris.

Establishment of fully human antibody production technology.

Establishment of BioWa, Inc. in the United States to promote Kyowa Hakko's therapeutic antibody business.

Japan’s first therapeutic antibody "tocilizumab" was approved.

The launch of Kirin Pharma Company, Limited to accompany the adoption by Kirin Brewery Company, Limited of a pure holding company system. Release of NESP®, a long-acting erythropoietic stimulating drug.

Release of REGPARA®, a drug for secondary hyperparathyroidism. Spun off its biochemical business, establishing Kyowa Hakko Bio Co., Ltd. Kyowa Hakko Kirin was formed through the merger of Kyowa Hakko Kogyo and Kirin Pharma.

Introduced 'Commitment to Life'.

Acquired ProStrakan Group plc.

Launch of Poteligeo® in Japan, a Therapeutic Antibody for Adult T-cell Leukemia-Lymphoma (ATL).

Launch of NOURIAST® tablets 20 mg in Japan, a novel antiparkinsonian agent.

ProStrakan Completes Acquisition of Archimedes. Launch of Sustained-Duration G-CSF Product G-LASTA® in Japan.

Rebranding Western Pharmaceutical Subsidiaries to 'Kyowa Kirin'. Launch of LUMICEF® for Psoriasis Treatment in Japan.

Crysvita® approved in the US and Europe for X-linked hypophosphatemia. Poteligeo® approved in the US and Europe for mycosis fungoides (MF) and Sézary syndrome (SS).

Trade name changed to Kyowa Kirin Co., Ltd. Crysvita® launched in Japan for FGF23-related Hypophosphatemic Rickets and Osteomalacia. Nourianz™ launched in the US for Parkinson's disease.

Poteligeo® launched in Europe for mycosis fungoides (MF) and Sézary syndrome (SS). Crysvita® approved in the US for tumor-induced osteomalacia (TIO).

New Vision toward 2030. Agreement with Amgen on KHK4083. Support for TCFD recommendations.

Global DE&I Statement adopted. Launch of G-Lasta® Subcutaneous Injection 3.6 mg BodyPod. Completion of Q-TOWER analysis facility.

More than 100 therapeutic antibodies have been approved in Japan, Europe, and the United States.

PHOZEVEL® approved in Japan. Acquisition of Orchard Therapeutics announced.

Lenmeldy™ approved and launched in the US. New biologics manufacturing plant planned in North Carolina. Collaboration with Kura Oncology on menin inhibitor ziftomenib.

Completion of HB7 Building at Takasaki Plant. FDA approval and US launch of KOMZIFTI™ (ziftomenib) for AML.